sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2f17 | PYI | Thiamin pyrophosphokinase 1 | 2.7.6.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2f17 | PYI | Thiamin pyrophosphokinase 1 | 2.7.6.2 | 1.000 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 1ig0 | VIB | Thiamine pyrophosphokinase | 2.7.6.2 | 0.459 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.453 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.441 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.440 |