sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 1.000 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.588 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.581 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.547 | |
| 4b6s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.535 | |
| 4b6r | 3DQ | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.517 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.507 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.498 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.480 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.471 | |
| 3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.467 | |
| 4l4x | NDP | AmphI | / | 0.463 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.458 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.455 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.455 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.454 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.448 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2y71 | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.443 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.442 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.442 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 5dp2 | NAP | CurF | / | 0.442 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 3n8n | N88 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 |