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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.630
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.611
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.585
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.545
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.539
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.539
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.529
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.489
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447