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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2bfpH4BPteridine reductase 11.5.1.33

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2bfpH4BPteridine reductase 11.5.1.331.000
1e92HBIPteridine reductase 11.5.1.330.859
2bf7HBIPteridine reductase 11.5.1.330.716
3h4vDVPPteridine reductase 11.5.1.330.664
2qhxFE1Pteridine reductase 11.5.1.330.654
2bfaCB3Pteridine reductase 11.5.1.330.624
2bfmTOPPteridine reductase 11.5.1.330.601
1e7wMTXPteridine reductase 11.5.1.330.492
1p33MTXPteridine reductase 11.5.1.330.486
2z7gEH9Adenosine deaminase3.5.4.40.470
1v7aFRCAdenosine deaminase3.5.4.40.466
1mxfMTXPutative pteridine reductase 2/0.464
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.453
2x9vTMQPteridine reductase/0.443
1umlFR4Adenosine deaminase3.5.4.40.442
2vz0D64Pteridine reductase/0.442
1o5rFR9Adenosine deaminase3.5.4.40.440