Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2b9jADPMitogen-activated protein kinase FUS32.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2b9jADPMitogen-activated protein kinase FUS32.7.11.241.000
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.680
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.611
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.536
4qnyANPMitogen activated protein kinase, putative/0.518
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.489
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.485
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.478
1qmzATPCyclin-dependent kinase 22.7.11.220.474
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.471
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.470
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.470
1jstATPCyclin-dependent kinase 22.7.11.220.469
3zh8C58Protein kinase C iota type2.7.11.130.467
1g5sI17Cyclin-dependent kinase 22.7.11.220.466
4xlvACPInsulin receptor2.7.10.10.464
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
5dnrATPAurora kinase A2.7.11.10.459
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.457
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.456
4ysjADPCalmodulin-like domain protein kinase/0.456
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.453
4fmqANPMitogen-activated protein kinase 12.7.11.240.453
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1ig1ANPDeath-associated protein kinase 12.7.11.10.452
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.451
3i60E86Mitogen-activated protein kinase 12.7.11.240.450
4ivb1J5Tyrosine-protein kinase JAK1/0.450
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.448
1pmn984Mitogen-activated protein kinase 102.7.11.240.448
4fv6E57Mitogen-activated protein kinase 12.7.11.240.448
4ii5ADPCyclin-dependent kinase 22.7.11.220.448
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.443
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
3c4zADPRhodopsin kinase/0.440
3s1h56ZCyclin-dependent kinase 22.7.11.220.440
5cnnANPEpidermal growth factor receptor2.7.10.10.440