Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2acsNAPAldose reductase1.1.1.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2acsNAPAldose reductase1.1.1.211.000
2iq0NAPAldose reductase1.1.1.210.761
1az2NAPAldose reductase1.1.1.210.746
1x96NAPAldose reductase1.1.1.210.739
1x98NAPAldose reductase1.1.1.210.713
2j8tNAPAldose reductase1.1.1.210.653
2acqNAPAldose reductase1.1.1.210.638
2acuNAPAldose reductase1.1.1.210.632
1z8aNAPAldose reductase1.1.1.210.609
3v36NAPAldose reductase1.1.1.210.597
1ah4NAPAldose reductase1.1.1.210.582
3q65NAPAldose reductase1.1.1.210.579
2pfhNDPAldose reductase1.1.1.210.574
2pf8NDPAldose reductase1.1.1.210.570
3q67NAPAldose reductase1.1.1.210.568
3h7rNAPAldo-keto reductase family 4 member C8/0.566
1adsNAPAldose reductase1.1.1.210.562
2pevNDPAldose reductase1.1.1.210.558
3o3rNAPAldose reductase-related protein 11.1.1.210.544
4g5dNDPProstaglandin F synthase1.1.1.1880.537
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.531
3qkzNAPAldose reductase-related protein 11.1.1.210.531
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.527
2hejNDPAldo-keto reductase family 1 member C211.1.10.523
4xo7NAPAldo-keto reductase family 1 member C2/0.506
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.504
4ijrNDPD-arabinose dehydrogenase [NAD(P)+] heavy chain1.1.1.1170.504
1zgdNAPChalcone reductase/0.503
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.499
1c9wNAPAldose reductase-related protein 2/0.493
1k8cNAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.493
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.493
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.493
4jtqNAPAldo-keto reductase family 1 member C2/0.491
1mi3NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.486
1s1rNAPAldo-keto reductase family 1 member C3/0.486
3wczNAPAldo-keto reductase AKR2E4/0.486
4pmjNAPPutative oxidoreductase/0.486
2hdjNDPAldo-keto reductase family 1 member C2/0.483
3wbwNDPPutative 2,5-diketo-D-gluconic acid reductase/0.479
2p5nNDPAldo-keto reductase family 1 member C211.1.10.475
4l1xNAPAldo-keto reductase family 1 member C2/0.472
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.470
1r38NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.469
4dz5NAPAldo-keto reductase family 1 member C3/0.469
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.467
1ye6NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.463
3wg6NDPNADPH-dependent conjugated polyketone reductase C1/0.462
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.460
1lqaNDPProtein tas/0.455
5c7hNDPPutative oxidoreductase/0.453
1z9aNADNAD(P)H-dependent D-xylose reductase1.1.1.3070.442
2bgsNDPAldose reductase1.1.1.210.441
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.441