sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 1.000 | |
| 3clt | FAD | Electron transfer flavoprotein subunit alpha | / | 0.468 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.468 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.466 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.463 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.454 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.452 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.452 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 1daa | PLP | D-alanine aminotransferase | 2.6.1.21 | 0.449 | |
| 1mf0 | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.449 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.446 | |
| 3c4v | LIP | D-inositol 3-phosphate glycosyltransferase | 2.4.1.250 | 0.445 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.445 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.444 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.444 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.444 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.444 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.443 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.441 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.441 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.440 |