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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2a8xFADDihydrolipoyl dehydrogenase1.8.1.4

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2a8xFADDihydrolipoyl dehydrogenase1.8.1.41.000
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.631
4jq9FADDihydrolipoyl dehydrogenase/0.493
3ic9FADPutative dihydrolipoamide dehydrogenase/0.470
3ladFADDihydrolipoyl dehydrogenase/0.468
3rnmFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.467
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.463
3urhFADDihydrolipoyl dehydrogenase/0.463
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.453
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.447
1jehFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.443
1lpfFADDihydrolipoyl dehydrogenase1.8.1.40.443