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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1xpqFADPolyamine oxidase FMS1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1xpqFADPolyamine oxidase FMS1/1.000
3cndFADPolyamine oxidase FMS1/0.605
3cn8FADPolyamine oxidase FMS1/0.590
4echFADPolyamine oxidase FMS1/0.579
3cntFADPolyamine oxidase FMS1/0.546
5l3dFADLysine-specific histone demethylase 1A10.533
2iw5FADLysine-specific histone demethylase 1A10.510
2uxxFAJLysine-specific histone demethylase 1A10.504
4fwjFADLysine-specific histone demethylase 1B10.503
4guuFA9Lysine-specific histone demethylase 1B10.499
3k7tFAD6-hydroxy-L-nicotine oxidase/0.489
1sezFADProtoporphyrinogen oxidase, mitochondrial1.3.3.40.474
2bacFADPutative aminooxidase/0.473
2yg7FADPutrescine oxidase/0.473
3kpfFADPolyamine oxidase1.5.3.140.473
4i58FADCyclohexylamine Oxidase/0.471
3bi2FADPolyamine oxidase FMS1/0.469
1h81FADPolyamine oxidase1.5.3.140.468
5g3tFDAFlavin-dependent L-tryptophan oxidase VioA/0.467
2babFADPutative aminooxidase/0.465
5g3sFDAFlavin-dependent L-tryptophan oxidase VioA/0.465
3zdnFADMonoamine oxidase N1.4.3.40.462
2ba9FADPutative aminooxidase/0.459
3rhaFDAPutrescine oxidase/0.457
2b9xFADPutative aminooxidase/0.456
1f8rFADL-amino-acid oxidase1.4.3.20.449
2b9yFADPutative aminooxidase/0.447
2yg4FADPutrescine oxidase/0.446
3bi5FADPolyamine oxidase FMS1/0.440
4gdpFADPolyamine oxidase FMS1/0.440