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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1xg5NAPDehydrogenase/reductase SDR family member 11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1xg5NAPDehydrogenase/reductase SDR family member 11/1.000
1xkqNDPUncharacterized protein/0.533
3l77NJPShort-chain alcohol dehydrogenase/0.527
4j7uNAPSepiapterin reductase1.1.1.1530.509
4j7xNAPSepiapterin reductase1.1.1.1530.507
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.498
4hwkNAPSepiapterin reductase1.1.1.1530.495
3rkuNAPNADP-dependent 3-hydroxy acid dehydrogenase/0.493
3tn7NJPShort-chain alcohol dehydrogenase/0.485
4bmvNAPShort-chain dehydrogenase/0.483
4qecNAPElxO/0.482
1oaaNAPSepiapterin reductase1.1.1.1530.480
1ipeNDPTropinone reductase 21.1.1.2360.475
2yutNAPPutative short-chain oxidoreductase/0.475
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.472
1ae1NAPTropinone reductase 1/0.469
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.469
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.467
4pvdNDPNADPH-dependent methylglyoxal reductase GRE2/0.464
4qedNAPElxO/0.462
1snyNAPLD36273p/0.460
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.459
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.455
3p19NDPPutative blue fluorescent protein/0.455
5idwNAPShort-chain dehydrogenase/reductase SDR/0.455
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.454
3ai2NDPNADPH-sorbose reductase/0.451
1x7gNAPPutative ketoacyl reductase1.3.10.446
1wntNAPL-xylulose reductase1.1.1.100.445
2jahNDPClavaldehyde dehydrogenase/0.444
1w4zNAPPutative ketoacyl reductase1.3.10.440
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3gy0NAPNAD(P)-dependent oxidoreductase/0.440
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.440
3toxNAPPutative oxidoreductase/0.440