sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uhj | CZB | Aequorin-2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1uhj | CZB | Aequorin-2 | / | 1.000 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.647 | |
| 1uhh | CZP | Aequorin-2 | / | 0.640 | |
| 4n1f | CZH | Obelin | / | 0.617 | |
| 4nqg | CZH | Mitrocomin | / | 0.616 | |
| 1jf0 | CZH | Obelin | / | 0.603 | |
| 1jf2 | CZH | Obelin | / | 0.590 | |
| 1qv1 | CZH | Obelin | / | 0.583 | |
| 1qv0 | CZH | Obelin | / | 0.581 | |
| 1el4 | CTZ | Obelin | / | 0.563 | |
| 1s36 | CEI | Obelin | / | 0.551 | |
| 4mrx | CZH | Obelin | / | 0.494 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.478 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.471 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.463 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.447 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.447 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.446 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 4ldl | XQC | Beta-2 adrenergic receptor | / | 0.446 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4lde | P0G | Beta-2 adrenergic receptor | / | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 |