sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 1.000 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.678 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.604 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.592 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.561 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.485 | |
| 1vgr | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.481 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.477 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.468 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.458 | |
| 5doz | NDP | JamJ | / | 0.458 | |
| 1c7o | PPG | Hemolysin | / | 0.457 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.457 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.454 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.453 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.452 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.451 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.451 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.450 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.450 | |
| 1dqa | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.449 | |
| 2e20 | B4P | Propionate kinase | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.449 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.448 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.448 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.448 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.447 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.446 | |
| 5dp2 | NAP | CurF | / | 0.446 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.445 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.444 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.444 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.443 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.442 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.442 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.442 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.442 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.440 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2q0g | UPU | Poly(A) polymerase, putative | / | 0.440 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.440 | |
| 3dr4 | G4M | GDP-perosamine synthase | / | 0.440 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.440 |