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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1sazACPProbable butyrate kinase 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1sazACPProbable butyrate kinase 2/1.000
3m4p4ADAsparaginyl-tRNA synthetase, putative/0.477
5kwvANPPantothenate synthetase/0.469
2zsdCOAPantothenate kinase2.7.1.330.465
5ah5LSSLeucine--tRNA ligase/0.460
4zwpM44Xaa-Pro dipeptidase3.4.13.90.459
2zsbADPPantothenate kinase2.7.1.330.455
3g0gRUMDipeptidyl peptidase 4/0.454
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.451
3n87N873-dehydroquinate dehydratase4.2.1.100.443
3pkaY02Methionine aminopeptidase 2/0.443
2bt4CA23-dehydroquinate dehydratase4.2.1.100.442
2zueANPArginine--tRNA ligase6.1.1.190.441
3juqAJDPhenazine biosynthesis protein A/B/0.441
1n2iPAJPantothenate synthetase6.3.2.10.440
4d2dALA_ALA_ALADi-or tripeptide:H+ symporter/0.440