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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/1.000
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.581.000
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.527
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.527
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.514
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.506
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.499
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.497
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.491
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.484
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.482
1s63778Protein farnesyltransferase subunit beta2.5.1.580.472
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.471
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.464
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.459
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.443
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.443
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.440