Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1q4j | GTX | Glutathione S-transferase | 2.5.1.18 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
1q4j | GTX | Glutathione S-transferase | 2.5.1.18 | 1.000 | |
3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.468 | |
3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
3vsw | R31 | Renin | 3.4.23.15 | 0.457 | |
4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
2g22 | 6IG | Renin | 3.4.23.15 | 0.453 | |
4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
1bim | 0QB | Renin | 3.4.23.15 | 0.452 | |
4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.451 | |
4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.448 | |
2f3f | AXF | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.446 | |
1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.445 | |
2g1o | 2IG | Renin | 3.4.23.15 | 0.445 | |
3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
2g1r | 3IG | Renin | 3.4.23.15 | 0.444 | |
3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.443 | |
2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.441 | |
4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
2ifa | FMN | Uncharacterized protein | / | 0.440 | |
2pj4 | 414 | Carboxypeptidase B | / | 0.440 | |
4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.440 | |
4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.440 |