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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.95

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.951.000
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.548
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.536
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.522
2pa3NAID-3-phosphoglycerate dehydrogenase1.1.1.950.520
2w2lNADD-mandelate dehydrogenase/0.503
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.480
3kb6NADD-lactate dehydrogenase/0.480
1ybaNADD-3-phosphoglycerate dehydrogenase1.1.1.950.471
2p9eNAID-3-phosphoglycerate dehydrogenase1.1.1.950.455
5bqfNAPProbable hydroxyacid dehydrogenase protein/0.454
4e5nNADPhosphonate dehydrogenase1.20.1.10.453
3zc3NAPFerredoxin--NADP reductase1.18.1.20.452
2g37FADProline dehydrogenase/0.450
3oetNADErythronate-4-phosphate dehydrogenase/0.450
2ydxNAPMethionine adenosyltransferase 2 subunit beta/0.448
2dbzNAPGlyoxylate reductase1.1.1.260.447
5dt9NADErythronate-4-phosphate dehydrogenase/0.444
2eklNADD-3-phosphoglycerate dehydrogenase/0.440
3u4cNDPNADPH-dependent reductase BacG/0.440