sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1oix | GDP | Ras-related protein Rab-11A |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1oix | GDP | Ras-related protein Rab-11A | / | 1.000 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.562 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.544 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.532 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.522 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.520 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.513 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.502 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.495 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.485 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.484 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.477 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.477 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.474 | |
| 3lbn | GNP | GTPase HRas | / | 0.469 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.469 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.469 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.468 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.465 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.462 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.462 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.461 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.460 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.459 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.457 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.457 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.455 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.455 | |
| 4v02 | ATP | Site-determining protein | / | 0.455 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.454 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.454 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.451 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.451 | |
| 3ddc | GNP | GTPase HRas | / | 0.449 | |
| 4nyi | GNP | GTPase HRas | / | 0.448 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.447 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.447 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.446 | |
| 2gvd | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.446 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.446 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.445 | |
| 3i3s | GNP | GTPase HRas | / | 0.445 | |
| 3oiv | GNP | GTPase HRas | / | 0.445 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.445 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.444 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.444 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.444 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.442 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.441 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.441 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.440 |