sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1og1 | TAD | T-cell ecto-ADP-ribosyltransferase 2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1og1 | TAD | T-cell ecto-ADP-ribosyltransferase 2 | / | 1.000 | |
| 1og4 | NAI | T-cell ecto-ADP-ribosyltransferase 2 | / | 0.541 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.457 | |
| 1gzf | NAD | Mono-ADP-ribosyltransferase C3 | 2.4.2 | 0.453 | |
| 1qs2 | NAD | Vip2Ac | / | 0.453 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 5bwm | NAI | ADP-ribosyltransferase | / | 0.447 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.443 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.443 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.442 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.440 |