Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1mmaADPMyosin-2 heavy chain

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1mmaADPMyosin-2 heavy chain/1.000
4pjkADPMyosin-2 heavy chain/0.594
3mykANPMyosin-2 heavy chain/0.572
1l2oADPMyosin heavy chain, striated muscle/0.542
1fmwATPMyosin-2 heavy chain/0.541
4pk4ADPUnconventional myosin-VI/0.518
1jx2ADPMyosin-2 heavy chain/0.514
1b7tADPMyosin heavy chain, striated muscle/0.512
4pjjADPUnconventional myosin-VI/0.508
1kqmANPMyosin heavy chain, striated muscle/0.493
4db1ANPMyosin-7/0.476
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.456
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.451
4pfpADPUnconventional myosin-VI/0.451
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
3w5uFADFerredoxin/0.446
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.442