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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.35

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.351.000
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.644
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.617
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.588
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.581
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.542
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.487
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
4uymVOR14-alpha sterol demethylase Cyp51B/0.449
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
3gobHXXDdmC/0.443
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.442
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
3r9uFADThioredoxin reductase/0.440