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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1i6kTYMTryptophan--tRNA ligase6.1.1.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1i6kTYMTryptophan--tRNA ligase6.1.1.21.000
1i6lTYMTryptophan--tRNA ligase6.1.1.20.637
2yy5WSATryptophan--tRNA ligase6.1.1.20.489
4j75TYMTryptophan--tRNA ligase/0.477
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.474
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
3jxeTYMTryptophan--tRNA ligase/0.447
3uylTYDProbable NDP-rhamnosyltransferase/0.440