Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1g6kNADGlucose 1-dehydrogenase1.1.1.47

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1g6kNADGlucose 1-dehydrogenase1.1.1.471.000
1gcoNADGlucose 1-dehydrogenase1.1.1.470.553
1rwbNADGlucose 1-dehydrogenase1.1.1.470.552
1geeNADGlucose 1-dehydrogenase1.1.1.470.537
3toxNAPPutative oxidoreductase/0.511
4hwkNAPSepiapterin reductase1.1.1.1530.501
1x7gNAPPutative ketoacyl reductase1.3.10.497
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.493
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.488
4j7uNAPSepiapterin reductase1.1.1.1530.487
1x7hNDPPutative ketoacyl reductase1.3.10.486
3lqfNADGalactitol dehydrogenase/0.485
1ae1NAPTropinone reductase 1/0.483
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.479
3vdqNAD3-hydroxybutyrate dehydrogenase/0.478
4j7xNAPSepiapterin reductase1.1.1.1530.478
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.477
1w4zNAPPutative ketoacyl reductase1.3.10.476
2bd0NAPSepiapterin reductase/0.476
5jlaNADPutative short-chain dehydrogenase/reductase/0.476
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.475
5idwNAPShort-chain dehydrogenase/reductase SDR/0.475
1xg5NAPDehydrogenase/reductase SDR family member 11/0.474
3f1kNAPUncharacterized oxidoreductase YciK10.474
2wdzNADGalactitol dehydrogenase/0.473
3bmoNAPPteridine reductase/0.471
4b79NADProbable short-chain dehydrogenase/0.471
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.470
4esoNAPPutative oxidoreductase/0.470
1snyNAPLD36273p/0.469
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.469
1ipeNDPTropinone reductase 21.1.1.2360.468
3l77NJPShort-chain alcohol dehydrogenase/0.468
2yutNAPPutative short-chain oxidoreductase/0.467
3p19NDPPutative blue fluorescent protein/0.467
4qecNAPElxO/0.466
1pr9NAPL-xylulose reductase1.1.1.100.465
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.464
3rkuNAPNADP-dependent 3-hydroxy acid dehydrogenase/0.463
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.463
4yaiNAIC alpha-dehydrogenase/0.463
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.462
1n5dNDPCarbonyl reductase [NADPH] 1/0.461
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.460
4bmvNAPShort-chain dehydrogenase/0.460
3ai2NDPNADPH-sorbose reductase/0.459
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.459
1oaaNAPSepiapterin reductase1.1.1.1530.458
1wntNAPL-xylulose reductase1.1.1.100.458
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.458
4nbwNADShort-chain dehydrogenase/reductase SDR/0.458
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.455
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.454
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.454
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.453
4yagNAIC alpha-dehydrogenase/0.453
1xkqNDPUncharacterized protein/0.452
4qedNAPElxO/0.451
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.449
2dteNAIGlucose 1-dehydrogenase related protein/0.448
3d3wNAPL-xylulose reductase1.1.1.100.448
3w8eNAD3-hydroxybutyrate dehydrogenase/0.448
4o0lNDPNADPH-dependent 3-quinuclidinone reductase/0.448
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.447
3ai3NDPNADPH-sorbose reductase/0.447
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.447
3tn7NJPShort-chain alcohol dehydrogenase/0.447
4dbzNDPPutative ketoacyl reductase1.3.10.447
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.445
4dc1NDPPutative ketoacyl reductase1.3.10.445
4dc0NDPPutative ketoacyl reductase1.3.10.443
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.442
3qrwNDPPutative ketoacyl reductase1.3.10.442
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.442
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.442
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.441
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.441
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440