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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1fmwATPMyosin-2 heavy chain

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1fmwATPMyosin-2 heavy chain/1.000
4pjkADPMyosin-2 heavy chain/0.573
1b7tADPMyosin heavy chain, striated muscle/0.540
1mmaADPMyosin-2 heavy chain/0.533
4pjjADPUnconventional myosin-VI/0.532
1jx2ADPMyosin-2 heavy chain/0.514
1kqmANPMyosin heavy chain, striated muscle/0.513
4db1ANPMyosin-7/0.510
3mykANPMyosin-2 heavy chain/0.507
4pk4ADPUnconventional myosin-VI/0.507
1l2oADPMyosin heavy chain, striated muscle/0.493