sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1err | RAL | Estrogen receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1err | RAL | Estrogen receptor | / | 1.000 | |
| 1yin | CM3 | Estrogen receptor | / | 0.617 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.572 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.569 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.554 | |
| 1uom | PTI | Estrogen receptor | / | 0.543 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.537 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.525 | |
| 2jfa | RAL | Estrogen receptor | / | 0.516 | |
| 1nde | MON | Estrogen receptor beta | / | 0.504 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.495 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.486 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.485 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.482 | |
| 4ivw | 1GJ | Estrogen receptor | / | 0.480 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.476 | |
| 4iv4 | 1GS | Estrogen receptor | / | 0.469 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.452 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 4iw6 | 1GU | Estrogen receptor | / | 0.452 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.450 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.450 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.449 | |
| 2pog | WST | Estrogen receptor | / | 0.448 | |
| 4iu7 | 1GM | Estrogen receptor | / | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.447 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.447 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.443 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.443 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.443 | |
| 1kyo | SMA | Cytochrome b | / | 0.441 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.440 |