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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.78

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.781.000
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.605
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.570
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.566
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.566
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.538
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.515
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.512
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.511
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.510
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.492
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.481
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.481
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.480
1w19T4P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.472
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.459
1w29TS16,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
1nqxRLP6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449