scPDB - Distribution of Binding site Similarity values of 1eg2 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1eg2	MTA	Modification methylase RsrI	2.1.1.72

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1eg2	MTA	Modification methylase RsrI	2.1.1.72	1.000
1nw5	SAM	Modification methylase RsrI	2.1.1.72	0.610
1nw6	SFG	Modification methylase RsrI	2.1.1.72	0.593
3swr	SFG	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.528
4gbe	SAH	DNA adenine methylase	2.1.1.72	0.513
3pt9	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.489
4rtn	SAH	DNA adenine methylase	2.1.1.72	0.488
4rtp	SAM	DNA adenine methylase	2.1.1.72	0.488
4rtl	SFG	DNA adenine methylase	2.1.1.72	0.484
4rtr	SAM	DNA adenine methylase	2.1.1.72	0.480
2ore	SAH	DNA adenine methylase	2.1.1.72	0.479
2dpm	SAM	Modification methylase DpnIIA	2.1.1.72	0.474
2yvl	SAM	tRNA (adenine(58)-N(1))-methyltransferase TrmI	/	0.472
2zzm	SAM	tRNA (guanine(37)-N1)-methyltransferase Trm5b	2.1.1.228	0.471
4rts	SAM	DNA adenine methylase	2.1.1.72	0.471
1e8z	STU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.468
4gol	SA8	DNA adenine methylase	2.1.1.72	0.468
4onj	SFG	DNA methyltransferase	/	0.466
3pt6	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.465
3qv2	SAH	5-cytosine DNA methyltransferase	/	0.465
4anx	534	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.464
4rtj	SFG	DNA adenine methylase	2.1.1.72	0.463
4rtm	SAM	DNA adenine methylase	2.1.1.72	0.458
2zif	SAM	Methyltransferase	/	0.457
5f8e	SAH	Possible transcriptional regulatory protein	/	0.457
1boo	SAH	Modification methylase PvuII	2.1.1.113	0.455
2pwy	SAH	tRNA (adenine(58)-N(1))-methyltransferase TrmI	2.1.1.220	0.455
1qyw	5SD	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.454
2g1p	SAH	DNA adenine methylase	2.1.1.72	0.454
4wxx	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.454
4dmg	SAM	Uncharacterized protein	/	0.453
4blw	SAH	Ribosomal RNA large subunit methyltransferase J	/	0.452
3v97	SAH	Ribosomal RNA large subunit methyltransferase K/L	2.1.1.173	0.451
3ldf	SAH	Uncharacterized protein	/	0.449
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.449
3ua3	SAH	Protein arginine N-methyltransferase 5	/	0.449
3fri	SAH	16S rRNA methylase	/	0.448
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.445
4rtk	SAH	DNA adenine methylase	2.1.1.72	0.444
1nw3	SAM	Histone-lysine N-methyltransferase, H3 lysine-79 specific	2.1.1.43	0.442
4uy6	SAH	Histidine N-alpha-methyltransferase	/	0.442
2zzn	SAM	tRNA (guanine(37)-N1)-methyltransferase Trm5b	2.1.1.228	0.441
4gb9	0WR	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.441
4rto	SFG	DNA adenine methylase	2.1.1.72	0.441
2ih2	NEA	Modification methylase TaqI	2.1.1.72	0.440
2yx1	SFG	tRNA (guanine(37)-N1)-methyltransferase Trm5b	2.1.1.228	0.440
3b89	5GP	16S rRNA methylase	/	0.440
3ou7	SAM	SAM-dependent methyltransferase	/	0.440
3rup	ADP	Biotin carboxylase	6.3.4.14	0.440
4nec	SAH	Putative SAM-dependent methyltransferase	/	0.440