Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1c0fATPMajor actin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1c0fATPMajor actin/1.000
4k42ADPActin, alpha skeletal muscle/0.616
1t44ATPActin, alpha skeletal muscle/0.608
1qz5ATPActin, alpha skeletal muscle/0.606
1lotATPActin, alpha skeletal muscle/0.605
3mn6ATPActin-5C/0.603
1rgiATPActin, alpha skeletal muscle/0.601
2q36ATPActin, alpha skeletal muscle/0.598
1dejATPMajor actin/0.591
5ce3ATPActin/0.588
1s22ATPActin, alpha skeletal muscle/0.587
4pkgATPActin, alpha skeletal muscle/0.585
3el2ATPActin-5C/0.584
1h1vATPActin, alpha skeletal muscle/0.582
3ffkATPActin, alpha skeletal muscle/0.576
4m63ATPActin-5C/0.575
3m6gATPActin, alpha skeletal muscle/0.571
4k41ATPActin, alpha skeletal muscle/0.571
4pkhADPActin, alpha skeletal muscle/0.571
2v51ATPActin, alpha skeletal muscle/0.570
3tu5ATPActin, alpha skeletal muscle/0.570
4pl8ATPActin, alpha skeletal muscle/0.569
4cbxATPActin-2/0.566
3a5mATPMajor actin/0.565
4jhdANPActin-5C/0.564
4ci6ATPActin/0.561
1nm1ATPMajor actin/0.558
3u9dATPActin, alpha skeletal muscle/0.551
3mn9ATPActin-5C/0.550
1eqyATPActin, alpha skeletal muscle/0.548
3eksATPActin-5C/0.547
1ijjATPActin, alpha skeletal muscle/0.546
2p9kATPActin-related protein 2/0.541
3mn7ATPActin-5C/0.540
1mduATPActin, alpha skeletal muscle/0.539
4pkiATPActin, alpha skeletal muscle/0.539
3w3dATPActin, gamma-enteric smooth muscle/0.538
4k43ADPActin, alpha skeletal muscle/0.536
1nmdATPMajor actin/0.535
1kxpATPActin, alpha skeletal muscle/0.528
2q97ATPActin, alpha skeletal muscle/0.524
1yxqATPActin, alpha skeletal muscle/0.522
4rwtANPActin-5C/0.522
3m1fATPActin, alpha skeletal muscle/0.516
2oanATPActin, cytoplasmic 1/0.508
3a5oATPMajor actin/0.503
3u4lATPActin, cytoplasmic 1/0.502
3ekuATPActin-5C/0.500
3chwATPMajor actin/0.485
3dawATPActin, alpha skeletal muscle/0.485
1nlvATPMajor actin/0.478
1wuaATPActin, alpha skeletal muscle/0.474
2a41ATPActin, alpha skeletal muscle/0.473
5eoyADPType 4 fimbrial biogenesis protein PilM/0.452