sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 1.000 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.496 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.484 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.481 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.480 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.476 | |
| 1vp5 | NAP | Oxidoreductase, aldo/keto reductase family | / | 0.472 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.472 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.470 | |
| 1mi3 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.465 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.463 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 1ye4 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.454 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 1az2 | NAP | Aldose reductase | 1.1.1.21 | 0.452 | |
| 4g5d | NDP | Prostaglandin F synthase | 1.1.1.188 | 0.452 | |
| 1zgd | NAP | Chalcone reductase | / | 0.451 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 1sm9 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.449 | |
| 1ads | NAP | Aldose reductase | 1.1.1.21 | 0.448 | |
| 5c7h | NDP | Putative oxidoreductase | / | 0.448 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 1k8c | NAP | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.446 | |
| 3wg6 | NDP | NADPH-dependent conjugated polyketone reductase C1 | / | 0.445 | |
| 2acq | NAP | Aldose reductase | 1.1.1.21 | 0.444 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 1z9a | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.442 | |
| 3q67 | NAP | Aldose reductase | 1.1.1.21 | 0.440 |