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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5a9s NAP Putative dehydrogenase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
5a9s NAPPutative dehydrogenase / 1.131
2hk9 NAPShikimate dehydrogenase (NADP(+)) / 0.708
2jkv NAP6-phosphogluconate dehydrogenase, decarboxylating 1.1.1.44 0.698
2hk9 ATRShikimate dehydrogenase (NADP(+)) / 0.697
3pdu NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.697
3zhb NAPPutative dehydrogenase / 0.695
3pef NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.677
1nyt NAPShikimate dehydrogenase (NADP(+)) / 0.672
3tri NAPPyrroline-5-carboxylate reductase / 0.672
2iyp A2P6-phosphogluconate dehydrogenase, decarboxylating 1.1.1.44 0.668
3w6u NAP6-phosphogluconate dehydrogenase, NAD-binding protein / 0.666
4qm6 GTPMetallophosphoesterase / 0.666
3ing NDPHomoserine dehydrogenase related protein / 0.665
1wp4 NDP3-hydroxyisobutyrate dehydrogenase / 0.664
1f9a ATPNicotinamide-nucleotide adenylyltransferase / 0.661
2cvz NDP3-hydroxyisobutyrate dehydrogenase / 0.660
2ev9 NAPShikimate dehydrogenase (NADP(+)) / 0.660
4hp8 NAP2-deoxy-D-gluconate 3-dehydrogenase / 0.659
4oqy NDP(S)-imine reductase / 0.659
4dmm NAP3-oxoacyl-[acyl-carrier-protein] reductase / 0.658
4xcv NDPProbable hydroxyacid dehydrogenase protein / 0.654
1n7g NDPGDP-mannose 4,6 dehydratase 2 4.2.1.47 0.650