Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4x28 FDA Acyl-CoA dehydrogenase FadE26

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4x28 FDAAcyl-CoA dehydrogenase FadE26 / 1.483
4x28 FDAAcyl-CoA dehydrogenase FadE27 / 1.483
4p13 FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.946
3owa FADAcyl-CoA dehydrogenase / 0.921
3mdd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.919
4m9a FDAAcyl-CoA dehydrogenase / 0.894
2vig FADShort-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.1 0.892
3pfd FDAAcyl-CoA dehydrogenase FadE25 / 0.892
1rx0 FADIsobutyryl-CoA dehydrogenase, mitochondrial 1.3.99 0.864
3nf4 FADAcyl-CoA dehydrogenase domain-containing protein / 0.862
2pg0 FADAcyl-CoA dehydrogenase / 0.842
5af7 FADAcyl-CoA dehydrogenase / 0.829
1egd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.821
3r7k FDAProbable acyl CoA dehydrogenase / 0.819
5ahs FADAcyl-CoA dehydrogenase / 0.816
2z1q FADAcyl-CoA dehydrogenase / 0.813
2ix5 FADAcyl-coenzyme A oxidase 4, peroxisomal 1.3.3.6 0.791
3p4t FAOPutative acyl-CoA dehydrogenase / 0.785
1ege FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.781
2fon FADAcyl-coenzyme A oxidase / 0.779
4iv6 FDAIsovaleryl-CoA dehydrogenase / 0.779
2d29 FADAcyl-CoA dehydrogenase / 0.776
3sf6 FDAGlutaryl-CoA dehydrogenase / 0.772
3mpj FADGlutaryl-CoA dehydrogenase 1.3.99.32 0.771
1siq FADGlutaryl-CoA dehydrogenase, mitochondrial 1.3.8.6 0.770
3mkh FADNitroalkane oxidase / 0.770
3djl FADPutative acyl-CoA dehydrogenase AidB 1.3.99 0.769
1u8v FAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase / 0.760
4irn FADAnaB / 0.749
5jsc FADPutative acyl-CoA dehydrogenase / 0.744
1buc FADAcyl-CoA dehydrogenase, short-chain specific 1.3.8.1 0.742
3mpi FADGlutaryl-CoA dehydrogenase 1.3.99.32 0.730
3u33 FADPutative acyl-CoA dehydrogenase AidB 1.3.99 0.730
4kto FADPutative isovaleryl-CoA dehydrogenase protein / 0.729
1t9g FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.721
1udy FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.709
1r2j FADFkbI / 0.708
2c12 FADNitroalkane oxidase 1.7.3.1 0.701
3fcj FADNitroalkane oxidase 1.7.3.1 0.699
2zaf FADNitroalkane oxidase 1.7.3.1 0.696
2yyl FAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component 1.14.14.9 0.694
2yyi FAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component 1.14.14.9 0.687
4eo3 FMNBacterioferritin comigratory protein/NADH dehydrogenase / 0.685
2reh FADNitroalkane oxidase 1.7.3.1 0.682
3ge6 FMNNitroreductase / 0.680
2isl FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.676
4y9l FADAcyl-CoA dehydrogenase family member 11 / 0.675
2dvl FADAcyl-CoA dehydrogenase / 0.674
3gag FMNPutative NADH dehydrogenase NAD(P)H nitroreductase / 0.674
3oib FDAPutative acyl-CoA dehydrogenase / 0.671
3hjk FADVivid PAS protein VVD / 0.667
2a1t FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.662
2isj FMN5,6-dimethylbenzimidazole synthase 1.13.11.79 0.662
2isk FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.662
4r81 FMNPredicted NADH dehydrogenase / 0.661
2bkj FMNNADPH-flavin oxidoreductase / 0.660
2eba FADPutative glutaryl-CoA dehydrogenase / 0.660
3ic9 FADPutative dihydrolipoamide dehydrogenase / 0.660
4kuk RBFPutative blue-light photoreceptor / 0.659
4opu FDAConserved Archaeal protein / 0.658
2c4c FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.656
4qly FMNEnone reductase CLA-ER / 0.655
1qr2 FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.654
2z6d FMNPhototropin-2 2.7.11.1 0.654
3gfd FMNIodotyrosine deiodinase 1 1.21.1.1 0.654
4hj6 FMNLOV protein / 0.654
2b3d FADModulator of drug activity B / 0.653
4ttc FMNIodotyrosine deiodinase 1 / 0.653
3lsh FADPyranose 2-oxidase / 0.652
3da1 FADGlycerol-3-phosphate dehydrogenase / 0.651
2i51 FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding / 0.650
3lcm FADPutative oxidoreductase / 0.650