Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4wrk DUP DUTPase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4wrk DUPDUTPase / 1.121
4gv8 DUPDUTPase / 0.982
2we3 DUTDeoxyuridine 5'-triphosphate nucleotidohydrolase / 0.880
2v9x DUTdCTP deaminase / 0.784
4a6a TTPdCTP deaminase 3.5.4.13 0.762
1snf UMPDeoxyuridine 5'-triphosphate nucleotidohydrolase 3.6.1.23 0.733
1xs4 DCPdCTP deaminase / 0.730
4xjc TTPdCTP deaminase / 0.730
2hxd DUPdCTP deaminase, dUMP-forming 3.5.4.30 0.710
2ol0 DUDDUTP pyrophosphatase / 0.701
2qxx TTPdCTP deaminase 3.5.4.13 0.699
1xje TTPVitamin B12-dependent ribonucleotide reductase / 0.682
4bri UNPEctonucleoside triphosphate diphosphohydrolase I / 0.679
1asc NPLAspartate aminotransferase 2.6.1.1 0.656
2w5a ADPSerine/threonine-protein kinase Nek2 2.7.11.1 0.655
2oke DUPDUTP pyrophosphatase / 0.652
2jj1 ADPATP synthase subunit alpha, mitochondrial / 0.651
2jj1 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.651
3ar4 ATPSarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.650