Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4o6f SAH N-lysine methyltransferase SMYD2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4o6f SAHN-lysine methyltransferase SMYD2 / 1.016
3tg4 SAMN-lysine methyltransferase SMYD2 / 0.973
5ex0 SAHHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.866
3ru0 SFGHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.854
3qwp SAMHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.843
3pdn SFGHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.837
5hq8 SAHHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.836
3rib SAHN-lysine methyltransferase SMYD2 / 0.825
3oxf SAHHistone-lysine N-methyltransferase SMYD3 2.1.1.43 0.824
3n71 SFGHistone-lysine N-methyltransferase Smyd1 / 0.797
3m53 SAHHistone-lysine N-methyltransferase SETD7 2.1.1.43 0.796
2h21 SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.793
4j83 SAMHistone-lysine N-methyltransferase SETD7 2.1.1.43 0.788
1n6c SAMHistone-lysine N-methyltransferase SETD7 2.1.1.43 0.787
1mlv SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.780
3cbp SFGHistone-lysine N-methyltransferase SETD7 2.1.1.43 0.769
2bqz SAHN-lysine methyltransferase KMT5A / 0.765
4o30 SAHProbable Histone-lysine N-methyltransferase ATXR5 2.1.1.43 0.757
4h12 SAHHistone-lysine N-methyltransferase SETD2 2.1.1.43 0.754
4ype SAMHistone-lysine N-methyltransferase ASH1L 2.1.1.43 0.753
1ozv SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.751
1p0y SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.743
5jhn SAMHistone-lysine N-methyltransferase EHMT2 / 0.742
4ypa SAMHistone-lysine N-methyltransferase ASH1L 2.1.1.43 0.738
2r3a SAMHistone-lysine N-methyltransferase SUV39H2 2.1.1.43 0.737
3ooi SAMHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific 2.1.1.43 0.736
3hna SAHHistone-lysine N-methyltransferase EHMT1 / 0.728
4qen SAHHistone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 2.1.1.43 0.728
2h2j SFGRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.724
2h23 SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic 2.1.1.127 0.716
2rfi SAHHistone-lysine N-methyltransferase EHMT1 / 0.714
5jin SAMHistone-lysine N-methyltransferase EHMT2 / 0.708
2igq SAHHistone-lysine N-methyltransferase EHMT1 / 0.700
3zno SE5D-amino-acid oxidase 1.4.3.3 0.698
2o8j SAHHistone-lysine N-methyltransferase EHMT2 / 0.696
3fpd SAHHistone-lysine N-methyltransferase EHMT1 / 0.694
5czy SAMEukaryotic huntingtin interacting protein B / 0.691
4kyh ZSTLactoylglutathione lyase 4.4.1.5 0.688
5jj0 SAMHistone-lysine N-methyltransferase EHMT2 / 0.688
4ynp SAMHistone-lysine N-methyltransferase ASH1L 2.1.1.43 0.683
4ypu SAMHistone-lysine N-methyltransferase ASH1L 2.1.1.43 0.683
3kmt SAHHistone H3K27 methylase / 0.681
3vuz K15Histone-lysine N-methyltransferase SETD7 2.1.1.43 0.677
3vv0 KH3Histone-lysine N-methyltransferase SETD7 2.1.1.43 0.675
4z4p SAHHistone-lysine N-methyltransferase 2D 2.1.1.43 0.671
3swc SAHHistone-lysine N-methyltransferase EHMT1 / 0.664
2rd5 NLGAcetylglutamate kinase, chloroplastic 2.7.2.8 0.656
3qt6 2P0Mevalonate diphosphate decarboxylase / 0.655
2p1p IACProtein TRANSPORT INHIBITOR RESPONSE 1 / 0.652
4au7 SAHHistone-lysine N-methyltransferase KMT5C 2.1.1.43 0.650