Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4jr3 KJR Epidermal growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4jr3 KJREpidermal growth factor receptor 2.7.10.1 1.052
4jq7 KJQEpidermal growth factor receptor 2.7.10.1 0.954
4jq8 KJ8Epidermal growth factor receptor 2.7.10.1 0.908
4jrv KJVEpidermal growth factor receptor 2.7.10.1 0.856
2itp AEEEpidermal growth factor receptor 2.7.10.1 0.789
1efz PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.744
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1m3q ANGN-glycosylase/DNA lyase 3.2.2 0.744
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.744
2puc GUNHTH-type transcriptional repressor PurR / 0.744
4ek9 EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.744
4i23 1C9Epidermal growth factor receptor 2.7.10.1 0.702
4wkq IREEpidermal growth factor receptor 2.7.10.1 0.699
3qud N3FMitogen-activated protein kinase 14 / 0.676
2zm1 KSFTyrosine-protein kinase Lck 2.7.10.2 0.664
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1ulb GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2pot GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2pwu GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2z1x PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4eh6 0ONMitogen-activated protein kinase 14 / 0.660
4h7z GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hqv QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hvx QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2y6o 1N1Ephrin type-A receptor 4 2.7.10.1 0.659
4xli 1N1Abelson tyrosine-protein kinase 2 2.7.10.2 0.659
2vwu 7X1Ephrin type-B receptor 4 2.7.10.1 0.655
3rgf BAXCyclin-dependent kinase 8 2.7.11.22 0.653
2x9f X9FEphrin type-B receptor 4 2.7.10.1 0.652
4i22 IREEpidermal growth factor receptor 2.7.10.1 0.650