Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4iwq 1FV Serine/threonine-protein kinase TBK1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4iwq 1FVSerine/threonine-protein kinase TBK1 2.7.11.1 1.058
4iwo 1H4Serine/threonine-protein kinase TBK1 2.7.11.1 0.806
4im0 1FVSerine/threonine-protein kinase TBK1 2.7.11.1 0.786
4e5i 0N9Polymerase acidic protein / 0.744
4dea NHIAurora kinase A 2.7.11.1 0.723
3uo5 0BXAurora kinase A 2.7.11.1 0.703
4im2 BX7Serine/threonine-protein kinase TBK1 2.7.11.1 0.684
2x4f 16XMyosin light chain kinase family member 4 2.7.11.1 0.677
3sw4 18KCyclin-dependent kinase 2 2.7.11.22 0.666
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.664
2xch CKG3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.655