Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4hvi 19S Tyrosine-protein kinase JAK3 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4hvi 19STyrosine-protein kinase JAK3 2.7.10.2 0.825
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
3zc6 VFCTyrosine-protein kinase JAK3 2.7.10.2 0.688
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.662
4e5f 0N7Polymerase acidic protein / 0.660
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.658
3blq ATPCyclin-dependent kinase 9 2.7.11.22 0.650