Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4gii 0X6 Non-receptor tyrosine-protein kinase TYK2 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4gii 0X6Non-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.922
4gih 0X5Non-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.870
4gj3 0XPNon-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.856
4gj2 0XHNon-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.844
4e5i 0N9Polymerase acidic protein / 0.744
4gmy 0X5Tyrosine-protein kinase JAK2 / 0.692
4mf0 29ZTyrosine-protein kinase ITK/TSK 2.7.10.2 0.683
4e6q 0NVTyrosine-protein kinase JAK2 / 0.663
4e5f 0N7Polymerase acidic protein / 0.660
4ji9 1M3Tyrosine-protein kinase JAK2 / 0.657
4f08 1RSTyrosine-protein kinase JAK2 / 0.653