Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fob 0US ALK tyrosine kinase receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4fob 0USALK tyrosine kinase receptor 2.7.10.1 1.083
4foc 0UUALK tyrosine kinase receptor 2.7.10.1 0.945
4fod 0UVALK tyrosine kinase receptor 2.7.10.1 0.802
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
3aox EMHALK tyrosine kinase receptor 2.7.10.1 0.723
2nru T12Interleukin-1 receptor-associated kinase 4 2.7.11.1 0.701
4e5f 0N7Polymerase acidic protein / 0.660
3bgq VX2Serine/threonine-protein kinase pim-1 2.7.11.1 0.658