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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4f86 SFG Geranyl diphosphate 2-C-methyltransferase 2.1.1.255

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4f86 SFGGeranyl diphosphate 2-C-methyltransferase 2.1.1.255 1.004
4r6x SAHPhosphoethanolamine N-methyltransferase / 0.711
3vc1 SAHGeranyl diphosphate 2-C-methyltransferase 2.1.1.255 0.693
3vc2 SAHGeranyl diphosphate 2-C-methyltransferase 2.1.1.255 0.692
4pne SAHMethyltransferase-like protein / 0.682
1xdu SFGAclacinomycin 10-hydroxylase RdmB 4.1.1 0.673
1qzz SAMAclacinomycin 10-hydroxylase RdmB 4.1.1 0.666
2zfu SAHRibosomal RNA-processing protein 8 / 0.664
1kph SAHCyclopropane mycolic acid synthase 1 2.1.1.79 0.658
3lcc SAHThiocyanate methyltransferase 1 / 0.657
2gs9 SAHUncharacterized protein / 0.653
2bzg SAHThiopurine S-methyltransferase 2.1.1.67 0.652
4mwz SAMPhosphoethanolamine N-methyltransferase, putative / 0.651