Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4er6 AW2 Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4er6 AW2Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 1.272
4er7 AW3Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.818
4eki 0QKHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.741
1nw3 SAMHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.740
3sr4 TT8Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.738
4ekg 0QJHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.718
3qow SAMHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.683
2ih2 NEAModification methylase TaqI 2.1.1.72 0.681
3rfx NADUronate dehydrogenase / 0.678
4yac NAIC alpha-dehydrogenase / 0.674
2hmv ADPKtr system potassium uptake protein A / 0.673
1aqi SAHModification methylase TaqI 2.1.1.72 0.665
2nyu SAMrRNA methyltransferase 2, mitochondrial / 0.660
2q1w NADPutative nucleotide sugar epimerase/ dehydratase / 0.659
2ih5 NEAModification methylase TaqI 2.1.1.72 0.658
2np7 NEAModification methylase TaqI 2.1.1.72 0.656
1i9g SAMtRNA (adenine(58)-N(1))-methyltransferase TrmI / 0.655
4ax8 SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD / 0.653
3bwc SAMSpermidine synthase, putative / 0.650