Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4e4l 0NH Tyrosine-protein kinase JAK1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4e4l 0NHTyrosine-protein kinase JAK1 / 0.887
4ei4 0Q2Tyrosine-protein kinase JAK1 / 0.793
4ivb 1J5Tyrosine-protein kinase JAK1 / 0.785
4ivd 15TTyrosine-protein kinase JAK1 / 0.780
4iva 1J5Tyrosine-protein kinase JAK2 / 0.774
4ivc 1J6Tyrosine-protein kinase JAK1 / 0.771
4f09 JAKTyrosine-protein kinase JAK2 / 0.741
4ehz JAKTyrosine-protein kinase JAK1 / 0.739
4e5w 0NTTyrosine-protein kinase JAK1 / 0.729
4f08 1RSTyrosine-protein kinase JAK2 / 0.728
4e6q 0NVTyrosine-protein kinase JAK2 / 0.717
4i5c C5ITyrosine-protein kinase JAK1 / 0.708
4e4m 0NHTyrosine-protein kinase JAK2 / 0.674
3qxp X64Cyclin-dependent kinase 2 2.7.11.22 0.658
4e4n 0NLTyrosine-protein kinase JAK1 / 0.656
4ccb OFGALK tyrosine kinase receptor 2.7.10.1 0.655
4ccu AWFALK tyrosine kinase receptor 2.7.10.1 0.655
3ral 04ZCyclin-dependent kinase 2 2.7.11.22 0.653