Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4dem YS4 Farnesyl pyrophosphate synthase 2.5.1.10

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4dem YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.339
4lfv YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.306
4h5d YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.265
4h5c YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.241
4h5e YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.201
3icz PB6Farnesyl pyrophosphate synthase / 0.990
4ga3 4GAFarnesyl pyrophosphate synthase 2.5.1.10 0.947
3dyh 721Farnesyl pyrophosphate synthase / 0.932
4dxj 0M9Farnesyl pyrophosphate synthase / 0.927
4l2x YL2Farnesyl pyrophosphate synthase 2.5.1.10 0.921
4dwb 0M7Farnesyl pyrophosphate synthase / 0.910
4q23 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.910
1rqj RISFarnesyl diphosphate synthase 2.5.1.10 0.892
4kqs RISFarnesyl pyrophosphate synthase 2.5.1.10 0.866
3egt 722Farnesyl pyrophosphate synthase / 0.864
1yv5 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.861
4nke RISFarnesyl pyrophosphate synthase 2.5.1.10 0.860
3ez3 ZOLFarnesyl pyrophosphate synthase, putative / 0.849
2o1o RISPutative farnesyl pyrophosphate synthase / 0.812
2z4w 749Geranylgeranyl pyrophosphate synthase / 0.790
1zw5 ZOLFarnesyl pyrophosphate synthase 2.5.1.10 0.782
2z52 H23Geranylgeranyl pyrophosphate synthase / 0.780
3ldw ZOLFarnesyl pyrophosphate synthase, putative / 0.780
3rbm B73Farnesyl pyrophosphate synthase, putative / 0.775
3rye UNRFarnesyl pyrophosphate synthase 2.5.1.10 0.775
5erm 210Fusicoccadiene synthase 4.2.3.43 0.760
2zev B71Geranylgeranyl pyrophosphate synthase / 0.759
1yq7 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.750
2f94 BFQFarnesyl pyrophosphate synthase 2.5.1.10 0.750
4jvj 1MVFarnesyl pyrophosphate synthase 2.5.1.10 0.728
2z4y 252Geranylgeranyl pyrophosphate synthase / 0.712
1khe GCPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.694
3oab DSTGeranyl diphosphate synthase large subunit / 0.688
2e8w IPEGeranylgeranyl pyrophosphate synthase / 0.685
2e91 ZOLGeranylgeranyl pyrophosphate synthase / 0.684
1esn ANPPantothenate kinase 2.7.1.33 0.675
3l77 NJPShort-chain alcohol dehydrogenase / 0.672
4h2i A125'-nucleotidase 3.1.3.5 0.666
3m0e ATPTranscriptional regulator (NtrC family) / 0.665
4typ AP5Adenylate kinase / 0.665
3rep ATPIntegrin-linked protein kinase 2.7.11.1 0.663
1lot ATPActin, alpha skeletal muscle / 0.662
1mmg AGSMyosin-2 heavy chain / 0.661
2nom DUTPoly(A) polymerase, putative / 0.659
4brd ANPEctonucleoside triphosphate diphosphohydrolase I / 0.659
1ky2 GNPGTP-binding protein YPT7 / 0.658
3lbi GNPGTPase HRas / 0.658
3rs5 GNPGTPase HRas / 0.657
3h4l ANPDNA mismatch repair protein PMS1 / 0.656
1mx0 ANPType 2 DNA topoisomerase 6 subunit B / 0.655
4bri UNPEctonucleoside triphosphate diphosphohydrolase I / 0.655
2y6p CTP3-deoxy-manno-octulosonate cytidylyltransferase 2.7.7.38 0.654
3w2w ATPCRISPR system Cmr subunit Cmr2 / 0.653
3k9l GNPGTPase HRas / 0.652
4qm6 GTPMetallophosphoesterase / 0.652
1bcp ATPPertussis toxin subunit 4 / 0.651
1bcp ATPPertussis toxin subunit 5 / 0.651
2q3f GNPRas-related GTP-binding protein D / 0.650
2qtv GNPSmall COPII coat GTPase SAR1 3.6.5 0.650
3mle ADPATP-dependent dethiobiotin synthetase BioD 6.3.3.3 0.650
4aff ATPNitrogen regulatory protein P-II / 0.650