Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4afj SJJ Glycogen synthase kinase-3 beta 2.7.11.26

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4afj SJJGlycogen synthase kinase-3 beta 2.7.11.26 0.913
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
3l1s Z92Glycogen synthase kinase-3 beta 2.7.11.26 0.707
2gdo 12CSerine/threonine-protein kinase Chk1 2.7.11.1 0.676
2o65 MYFSerine/threonine-protein kinase pim-1 2.7.11.1 0.663
4e5f 0N7Polymerase acidic protein / 0.660
2iwx M1SATP-dependent molecular chaperone HSP82 / 0.659
2cgf P2NATP-dependent molecular chaperone HSP82 / 0.658
2iws NP4ATP-dependent molecular chaperone HSP82 / 0.652
2zdt 46CMitogen-activated protein kinase 10 2.7.11.24 0.652
3lkh LT6Genome polyprotein 2.7.7.48 0.651
1ke5 LS1Cyclin-dependent kinase 2 2.7.11.22 0.650
4g1w G1WMitogen-activated protein kinase 8 2.7.11.24 0.650