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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4a4l 939 Serine/threonine-protein kinase PLK1 2.7.11.21

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4a4l 939Serine/threonine-protein kinase PLK1 2.7.11.21 1.168
2yac 937Serine/threonine-protein kinase PLK1 2.7.11.21 1.020
4a4o 664Serine/threonine-protein kinase PLK1 2.7.11.21 0.996
4c3f 7KWTyrosine-protein kinase Lck 2.7.10.2 0.679
2xnb Y8LCyclin-dependent kinase 2 2.7.11.22 0.663
2c5n CK8Cyclin-dependent kinase 2 2.7.11.22 0.657
2x1n X1NCyclin-dependent kinase 2 2.7.11.22 0.656
1m52 P17Tyrosine-protein kinase ABL1 2.7.10.2 0.653