Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4a06 ATP 3-phosphoinositide-dependent protein kinase 1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4a06 ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.839
2biy ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.700
4crs AGSSerine/threonine-protein kinase N2 2.7.11.13 0.661
3hrc ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.654
2itx ANPEpidermal growth factor receptor 2.7.10.1 0.653
3hko ANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands / 0.653
2xf3 J01Uncharacterized protein / 0.652