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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3w32 W32 Epidermal growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3w32 W32Epidermal growth factor receptor 2.7.10.1 1.275
3poz 03PEpidermal growth factor receptor 2.7.10.1 0.995
3w33 W19Epidermal growth factor receptor 2.7.10.1 0.949
1xkk FMMEpidermal growth factor receptor 2.7.10.1 0.768
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4hjo AQ4Epidermal growth factor receptor 2.7.10.1 0.674
3fi3 JK2Mitogen-activated protein kinase 10 2.7.11.24 0.666
4e5f 0N7Polymerase acidic protein / 0.660
3ue4 DB8Tyrosine-protein kinase ABL1 2.7.10.2 0.652
2b1p AIZMitogen-activated protein kinase 10 2.7.11.24 0.650