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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3vf9 477 Tyrosine-protein kinase SYK 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3vf9 477Tyrosine-protein kinase SYK 2.7.10.2 0.878
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
3vf8 0JETyrosine-protein kinase SYK 2.7.10.2 0.729
3v5j 0F2Tyrosine-protein kinase ITK/TSK 2.7.10.2 0.682
2c3k ABOSerine/threonine-protein kinase Chk1 2.7.11.1 0.676
3v5l 0G1Tyrosine-protein kinase ITK/TSK 2.7.10.2 0.672
2w1h L0FCyclin-dependent kinase 2 2.7.11.22 0.671
3vid 4TTVascular endothelial growth factor receptor 2 2.7.10.1 0.667
4e5f 0N7Polymerase acidic protein / 0.660