Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3veu 0GO Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3veu 0GOBeta-secretase 1 3.4.23.46 1.173
3k5g BJCBeta-secretase 1 3.4.23.46 1.025
3dv5 BAVBeta-secretase 1 3.4.23.46 0.955
4exg 916Beta-secretase 1 3.4.23.46 0.946
2vnn CM7Beta-secretase 1 3.4.23.46 0.942
2wf2 ZY2Beta-secretase 1 3.4.23.46 0.941
4lxk 1YTBeta-secretase 1 3.4.23.46 0.934
2xfk AA9Beta-secretase 1 3.4.23.46 0.929
2vnm CM8Beta-secretase 1 3.4.23.46 0.928
4lxa 1YSBeta-secretase 1 3.4.23.46 0.928
3k5c 0BIBeta-secretase 1 3.4.23.46 0.925
2xfi XFIBeta-secretase 1 3.4.23.46 0.923
4ewo 996Beta-secretase 1 3.4.23.46 0.919
2wf0 ZY0Beta-secretase 1 3.4.23.46 0.915
2iqg F2IBeta-secretase 1 3.4.23.46 0.908
2viy VG3Beta-secretase 1 3.4.23.46 0.906
2vj7 VG6Beta-secretase 1 3.4.23.46 0.906
3lpj Z75Beta-secretase 1 3.4.23.46 0.906
2viz VG4Beta-secretase 1 3.4.23.46 0.899
2hiz LIJBeta-secretase 1 3.4.23.46 0.897
4k9h 1QUBeta-secretase 1 3.4.23.46 0.895
3ohh 3HHBeta-secretase 1 3.4.23.46 0.887
2vj6 VG5Beta-secretase 1 3.4.23.46 0.883
2xfj VG5Beta-secretase 1 3.4.23.46 0.882
2wf1 ZY1Beta-secretase 1 3.4.23.46 0.879
2wf3 ZY3Beta-secretase 1 3.4.23.46 0.877
3r2f PB0Beta-secretase 1 3.4.23.46 0.874
3nsh 957Beta-secretase 1 3.4.23.46 0.871
4i0i 957Beta-secretase 1 3.4.23.46 0.871
2wez ZYEBeta-secretase 1 3.4.23.46 0.869
2b8v 3BNBeta-secretase 1 3.4.23.46 0.866
3ohf 3HFBeta-secretase 1 3.4.23.46 0.864
4lxm 1YUBeta-secretase 1 3.4.23.46 0.863
3cic 316Beta-secretase 1 3.4.23.46 0.862
4fco 0U4Beta-secretase 1 3.4.23.46 0.861
2p83 MR0Beta-secretase 1 3.4.23.46 0.858
4i0h 1BLBeta-secretase 1 3.4.23.46 0.855
4dus 0MPBeta-secretase 1 3.4.23.46 0.854
2b8l 5HABeta-secretase 1 3.4.23.46 0.850
2vij C44Beta-secretase 1 3.4.23.46 0.850
3qi1 C6ABeta-secretase 1 3.4.23.46 0.850
2p8h MY9Beta-secretase 1 3.4.23.46 0.848
4ke0 1R8Beta-secretase 1 3.4.23.46 0.845
2vj9 VG7Beta-secretase 1 3.4.23.46 0.842
4dh6 0KNBeta-secretase 1 3.4.23.46 0.841
3vg1 0GTBeta-secretase 1 3.4.23.46 0.837
4k8s 1QTBeta-secretase 1 3.4.23.46 0.834
3pi5 3P5Beta-secretase 1 3.4.23.46 0.833
3vf3 0GSBeta-secretase 1 3.4.23.46 0.833
4d89 BXDBeta-secretase 1 3.4.23.46 0.829
3qbh QBHBeta-secretase 1 3.4.23.46 0.828
4ke1 1R6Beta-secretase 1 3.4.23.46 0.818
3cid 318Beta-secretase 1 3.4.23.46 0.806
3pww ROCEndothiapepsin 3.4.23.22 0.806
2vkm BSDBeta-secretase 1 3.4.23.46 0.801
2fdp FRPBeta-secretase 1 3.4.23.46 0.777
4i0j 842Beta-secretase 1 3.4.23.46 0.772
3dm6 757Beta-secretase 1 3.4.23.46 0.764
1od1 0QSEndothiapepsin 3.4.23.22 0.736
1ppk IVVPenicillopepsin-1 3.4.23.20 0.735
3dv1 AR9Beta-secretase 1 3.4.23.46 0.733
2f3e AXQBeta-secretase 1 3.4.23.46 0.731
3lpi Z74Beta-secretase 1 3.4.23.46 0.731
1bxq PP8Penicillopepsin-1 3.4.23.20 0.724
2g94 ZPQBeta-secretase 1 3.4.23.46 0.722
2oah QINBeta-secretase 1 3.4.23.46 0.719
2jji 0QSEndothiapepsin 3.4.23.22 0.717
3k5f AYHBeta-secretase 1 3.4.23.46 0.717
3cib 314Beta-secretase 1 3.4.23.46 0.715
2jjj 0QSEndothiapepsin 3.4.23.22 0.714
3n4l 842Beta-secretase 1 3.4.23.46 0.704
1gvw 0EMEndothiapepsin 3.4.23.22 0.703
1rne C60Renin 3.4.23.15 0.698
2vie VG0Beta-secretase 1 3.4.23.46 0.698
3lpk Z76Beta-secretase 1 3.4.23.46 0.696
1gvv 0GMEndothiapepsin 3.4.23.22 0.691
2web PP4Penicillopepsin-1 3.4.23.20 0.690
1e81 M91Endothiapepsin 3.4.23.22 0.688
3duy AFJBeta-secretase 1 3.4.23.46 0.685
4dpi 0N1Beta-secretase 1 3.4.23.46 0.685
1w51 L01Beta-secretase 1 3.4.23.46 0.682
1e82 M90Endothiapepsin 3.4.23.22 0.677
2qzl IXSBeta-secretase 1 3.4.23.46 0.676
3k5d XLIBeta-secretase 1 3.4.23.46 0.676
1b6p PI7Gag-Pol polyprotein 3.4.23.16 0.670
1gvt 2ZSEndothiapepsin 3.4.23.22 0.669
1b6k PI5Gag-Pol polyprotein 3.4.23.16 0.668
3i25 MV7Beta-secretase 1 3.4.23.46 0.668
4dpf 0LGBeta-secretase 1 3.4.23.46 0.665
1psa 0ZLPepsin A 3.4.23.1 0.656
2hm1 LIQBeta-secretase 1 3.4.23.46 0.654
2g20 L1ARenin 3.4.23.15 0.653
3ixk 929Beta-secretase 1 3.4.23.46 0.653
3d91 REMRenin 3.4.23.15 0.651
3ixj 586Beta-secretase 1 3.4.23.46 0.650