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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qbh QBH Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3qbh QBHBeta-secretase 1 3.4.23.46 1.234
3pi5 3P5Beta-secretase 1 3.4.23.46 1.024
4lxa 1YSBeta-secretase 1 3.4.23.46 0.945
4lxk 1YTBeta-secretase 1 3.4.23.46 0.927
4lxm 1YUBeta-secretase 1 3.4.23.46 0.880
3lpj Z75Beta-secretase 1 3.4.23.46 0.879
3vf3 0GSBeta-secretase 1 3.4.23.46 0.879
3cib 314Beta-secretase 1 3.4.23.46 0.873
4d89 BXDBeta-secretase 1 3.4.23.46 0.857
3lpk Z76Beta-secretase 1 3.4.23.46 0.849
3cic 316Beta-secretase 1 3.4.23.46 0.846
3dv5 BAVBeta-secretase 1 3.4.23.46 0.843
3k5g BJCBeta-secretase 1 3.4.23.46 0.838
3veu 0GOBeta-secretase 1 3.4.23.46 0.828
2hm1 LIQBeta-secretase 1 3.4.23.46 0.822
2wf2 ZY2Beta-secretase 1 3.4.23.46 0.814
3k5c 0BIBeta-secretase 1 3.4.23.46 0.811
3lpi Z74Beta-secretase 1 3.4.23.46 0.806
2vnm CM8Beta-secretase 1 3.4.23.46 0.795
4ewo 996Beta-secretase 1 3.4.23.46 0.791
3r2f PB0Beta-secretase 1 3.4.23.46 0.789
2vj7 VG6Beta-secretase 1 3.4.23.46 0.788
2xfj VG5Beta-secretase 1 3.4.23.46 0.787
3cid 318Beta-secretase 1 3.4.23.46 0.787
4k9h 1QUBeta-secretase 1 3.4.23.46 0.787
2iqg F2IBeta-secretase 1 3.4.23.46 0.785
4exg 916Beta-secretase 1 3.4.23.46 0.785
2vnn CM7Beta-secretase 1 3.4.23.46 0.784
2vj6 VG5Beta-secretase 1 3.4.23.46 0.783
3ohh 3HHBeta-secretase 1 3.4.23.46 0.780
4dpf 0LGBeta-secretase 1 3.4.23.46 0.780
2wf1 ZY1Beta-secretase 1 3.4.23.46 0.768
2wf0 ZY0Beta-secretase 1 3.4.23.46 0.767
1w51 L01Beta-secretase 1 3.4.23.46 0.762
4dpi 0N1Beta-secretase 1 3.4.23.46 0.760
2xfi XFIBeta-secretase 1 3.4.23.46 0.759
4k8s 1QTBeta-secretase 1 3.4.23.46 0.753
2xfk AA9Beta-secretase 1 3.4.23.46 0.752
2wez ZYEBeta-secretase 1 3.4.23.46 0.751
2viy VG3Beta-secretase 1 3.4.23.46 0.750
2vie VG0Beta-secretase 1 3.4.23.46 0.749
4fco 0U4Beta-secretase 1 3.4.23.46 0.742
2viz VG4Beta-secretase 1 3.4.23.46 0.739
4ke1 1R6Beta-secretase 1 3.4.23.46 0.738
3qi1 C6ABeta-secretase 1 3.4.23.46 0.737
3ohf 3HFBeta-secretase 1 3.4.23.46 0.736
2b8v 3BNBeta-secretase 1 3.4.23.46 0.735
2p83 MR0Beta-secretase 1 3.4.23.46 0.734
2vij C44Beta-secretase 1 3.4.23.46 0.729
3nsh 957Beta-secretase 1 3.4.23.46 0.727
4dh6 0KNBeta-secretase 1 3.4.23.46 0.727
4i0i 957Beta-secretase 1 3.4.23.46 0.727
3tpr 5HABeta-secretase 1 3.4.23.46 0.722
2vj9 VG7Beta-secretase 1 3.4.23.46 0.721
4ke0 1R8Beta-secretase 1 3.4.23.46 0.720
2wf4 ZY4Beta-secretase 1 3.4.23.46 0.719
2b8l 5HABeta-secretase 1 3.4.23.46 0.713
2hiz LIJBeta-secretase 1 3.4.23.46 0.703
2wf3 ZY3Beta-secretase 1 3.4.23.46 0.703
3n4l 842Beta-secretase 1 3.4.23.46 0.681
2p8h MY9Beta-secretase 1 3.4.23.46 0.676
3vg1 0GTBeta-secretase 1 3.4.23.46 0.659
2oah QINBeta-secretase 1 3.4.23.46 0.658
3uhl 2NCGag-Pol polyprotein 3.4.23.16 0.655
2fdp FRPBeta-secretase 1 3.4.23.46 0.654