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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3p7a P7A Mitogen-activated protein kinase 14

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3p7a P7AMitogen-activated protein kinase 14 / 1.072
3p7b P7BMitogen-activated protein kinase 14 / 0.887
3nnx EDDMitogen-activated protein kinase 14 / 0.838
3p5k P5KMitogen-activated protein kinase 14 / 0.830
2yiw YIWMitogen-activated protein kinase 14 / 0.813
2puu G2GMitogen-activated protein kinase 14 / 0.811
3hv7 1AUMitogen-activated protein kinase 14 / 0.798
3npc B96Mitogen-activated protein kinase 9 2.7.11.24 0.787
3gi3 B10Mitogen-activated protein kinase 14 / 0.770
1w82 L10Mitogen-activated protein kinase 14 / 0.748
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1kv2 B96Mitogen-activated protein kinase 14 / 0.739
3p7c P7CMitogen-activated protein kinase 14 / 0.736
2yis YISMitogen-activated protein kinase 14 / 0.735
1kv1 BMUMitogen-activated protein kinase 14 / 0.704
1wbv LI3Mitogen-activated protein kinase 14 / 0.699
3uvr 06FMitogen-activated protein kinase 14 / 0.689
3gcu R48Mitogen-activated protein kinase 14 / 0.683
3nww 3NWMitogen-activated protein kinase 14 / 0.682
3hv3 R49Mitogen-activated protein kinase 14 / 0.680
3p79 P79Mitogen-activated protein kinase 14 / 0.678
1wbs LI2Mitogen-activated protein kinase 14 / 0.668
3gcq 1BUMitogen-activated protein kinase 14 / 0.666
3lfe Z84Mitogen-activated protein kinase 14 / 0.664
4e5f 0N7Polymerase acidic protein / 0.660
1wbt WBTMitogen-activated protein kinase 14 / 0.658
3hv4 L51Mitogen-activated protein kinase 14 / 0.656
3hv5 R24Mitogen-activated protein kinase 14 / 0.656
3hv6 R39Mitogen-activated protein kinase 14 / 0.655
3p78 P78Mitogen-activated protein kinase 14 / 0.655
3qri 919Tyrosine-protein kinase ABL1 2.7.10.2 0.653
4f7n 0SVCyclin-dependent kinase 8 2.7.11.22 0.652
3k3j F4CMitogen-activated protein kinase 14 / 0.651