sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3l67 | FMN | Xenobiotic reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3l67 | FMN | Xenobiotic reductase | / | 1.274 | |
| 4utm | FNR | Xenobiotic reductase | / | 1.226 | |
| 3l5l | FMN | Xenobiotic reductase | / | 1.225 | |
| 4uth | FMN | Xenobiotic reductase | / | 1.221 | |
| 4utk | FNR | Xenobiotic reductase | / | 1.184 | |
| 2h8x | FMN | XenA | / | 1.181 | |
| 3n14 | FMN | Xenobiotic reductase | / | 1.165 | |
| 4utl | FNR | Xenobiotic reductase | / | 1.156 | |
| 3n19 | FNR | Xenobiotic reductase | / | 1.149 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 1.011 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 1.009 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 1.001 | |
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.978 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.966 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.958 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.945 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.944 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.941 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.941 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.931 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.931 | |
| 3hf3 | FMN | Chromate reductase | / | 0.927 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.927 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.925 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.922 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.920 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.918 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.917 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.909 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.909 | |
| 1gwj | FMN | Morphinone reductase | / | 0.907 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.907 | |
| 4e2d | FMN | Dehydrogenase | / | 0.907 | |
| 4jic | FMN | GTN Reductase | / | 0.906 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.904 | |
| 5cpm | FNR | NADH:flavin oxidoreductase | / | 0.904 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.902 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.901 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.899 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.898 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.897 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.894 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.893 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.890 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.887 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.886 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.884 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.883 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.883 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.880 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.872 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.872 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.871 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.869 | |
| 1djq | FMN | Trimethylamine dehydrogenase | 1.5.8.2 | 0.859 | |
| 4e2b | FMN | Dehydrogenase | / | 0.854 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.853 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.850 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.848 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.847 | |
| 2zfa | FMN | Lactate oxidase | / | 0.846 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.846 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.841 | |
| 2nli | FMN | Lactate oxidase | / | 0.838 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.832 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.832 | |
| 2j6x | FMN | Lactate oxidase | / | 0.828 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.828 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.827 | |
| 1jub | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.826 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.824 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.814 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.810 | |
| 2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.807 | |
| 1ofd | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.806 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.802 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.796 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.794 | |
| 4yl2 | FMN | Lactate oxidase | / | 0.786 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.782 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.780 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.774 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.773 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.772 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.771 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.768 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.768 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.767 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.763 | |
| 4cw5 | FMN | DfnA | / | 0.763 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.762 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.759 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.758 | |
| 1ofe | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.755 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.754 | |
| 1h7w | FMN | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.751 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.750 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.746 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.743 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.738 | |
| 4z9r | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.734 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.729 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.729 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.726 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.716 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.713 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.710 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.709 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.704 | |
| 2du2 | FMN | Lactate oxidase | / | 0.703 | |
| 3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.700 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.698 | |
| 2e77 | FMN | Lactate oxidase | / | 0.696 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.688 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.686 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.684 | |
| 5ebu | FMN | Lactate oxidase | / | 0.684 | |
| 4rje | FNR | Lactate oxidase | / | 0.683 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.682 | |
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.682 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.681 | |
| 5a89 | FMN | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.681 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.680 | |
| 1llw | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.679 | |
| 3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.677 | |
| 3bw3 | FMN | Putative 2-nitropropane dioxygenase | / | 0.676 | |
| 4z38 | FMN | MlnA | / | 0.676 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.673 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.673 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.672 | |
| 4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.672 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.672 | |
| 1qr2 | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.670 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.668 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.668 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.666 | |
| 3w77 | FMN | FMN-dependent NADH-azoreductase | / | 0.666 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.665 | |
| 3n39 | FMN | Protein NrdI | / | 0.665 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.662 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.662 | |
| 4j8p | FMN | Flavodoxin | / | 0.661 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.660 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.656 | |
| 4n65 | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.656 | |
| 1zwl | FMN | NAD(P)H dehydrogenase (quinone) | 1.6.5.2 | 0.652 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.652 | |
| 3klb | FMN | Uncharacterized protein | / | 0.652 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.652 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.651 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.651 |